Locked Nucleic Acid (LNA) : High affinity targeting of RNA for diagnostics and therapeutics
Kauppinen S, Vester B and Wengel J
Drug Discov Today Technol 2005 2: 287-90 |
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MicroRNA expression in zebrafish embryonic development
Wienholds E, Kloosterman WP, Miska E, Alvarez-Saavedra E, Berezikov E, de Bruijn E, Horvitz RH, Kauppinen S and Plasterk RHA
2005 Science 309:310-311 |
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LNA: Fra dansk grundforskning til første kliniske forsøg
T Koch
Dansk Kemi 2005 86: 1-5 |
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Evaluation of LNA-modified DNAzymes targeting a single nucleotide polymorphism in the large subunit of RNA Polymerase II
Fluiter K, Frieden M, Vreijling J, Koch T and Baas F
Oligonucleotides 2005 15(4): 246-254 |
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On the in vitro and in vivo properties of four Locked Nucleic Acid nucleotides incorporated into an Anti-H-Ras antisense oligonucleotide
Fluiter K, Frieden M, Vreijling J , Rosenbohm C, De Wissel MB, Christensen SM, Koch T, Orum H and Baas F
ChemBioChem 2005 6(6): 1104-1109 |
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Locked Nucleic Acid (LNA) mediated improvements in siRNA stability and functionality
Elmén J, Thonberg H, Ljungberg K , Frieden M, Westergaard M, Xu Y, Wahren B, Liang Z, Orum H, Koch T and Wahlestedt C
Nucleic Acids Research 2005 33(1): 439-447 |
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Engineering genomics RNA antagonists-a new class of antisense drugs
Orum H
Eng Med Biol Mag 2005 24(4): 81-87 |
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