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Move your mouse over the questions on the left hand side to view the answers. |
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What kind of Company is Santaris Pharma?
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Santaris Pharma is a biopharmaceutical company developing novel drug candidates for targeted RNA-therapy based on its proprietary LNA chemistry.
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Is Santaris Pharma represented outside Denmark?
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Yes, Santaris Pharma has subsidiary in San Diego California, USA
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What is the financial situation of Santaris Pharma
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The Company is well financed through 2010.
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Who are Santaris Pharma's pharmaceutical partners?
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Enzon Pharmaceuticals, GlaxoSmithKline and Wyeth Pharmaceuticals.
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What is RNA?
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RNA (ribonucleic acid) is a long linear polymer of nucleotides found primarily in the cytoplasm of a cell where it is associated with microsomes; it transmits genetic information from DNA to the cytoplasm and controls certain chemical processes in the cell)
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What is antisense?
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Antisense is a molecule which interacts with a complementary strand of nucleic acids (RNA) to suppress its transcription.
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What makes Santaris Pharma different?
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Santaris Pharma holds all international therapeutic rights to the basic LNA chemistry. LNA is the chemistry of choice for RNA-targeting therapeutics.
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Why is RNA a good target for therapeutics?
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There is a linkage between genes and diseases, and RNA-targeting is the most direct way to translate this genomic information into drugs. LNA chemistry is the chemistry-of-choice for RNA-targeting therapeutics.
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What is microRNA?
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microRNAs are a relatively newly discovered class of short RNAs that function naturally in cells to fine-tune the expression of genes. As a novel class of targets they have created significant excitement in the scientific community and drug industry where they are increasingly considered promising therapeutic intervention points.
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Who are the owners of Santaris Pharma?
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A group of international investors own Santaris Pharma. The group comprises Forbion Capital Partners, Bankinvest, Innovations Capital, Sunstone Capital, Seventure, Global lifescience ventures, LD, Novo, Teknoinvest and Gilde Healthcare Partners.
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Who is the Chairman of the Board of the company?
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Flemming Ørnskov, President, Pharmaceuticals and OTC, Bausch & Lomb, Inc.
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Who is the CEO of the Company?
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Søren Tulstrup is the CEO of Santaris Pharma.
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What are the Company's core competences?
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Santaris Pharma's unique and proprietary LNA Drug Platform and an exceptionally effective and efficient Drug Discovery Engine.
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What kind of technology is LNA?
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LNA, Locked Nucleic Acid, technology is an antisense technology which is used to develop novel RNA-targeted therapeutics. LNA molecules are built into synthetic DNA oligonucleotides that have the ability to specifically bind to complementary sequences of messengerRNAs and microRNAs.
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How do LNA-based RNA drugs differ from other approaches?
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LNA-based drugs are characterised by a number of unique properties, among which are high biostability and an unprecedented target affinity, which enable strong pharmacological activity to be packed into metabolically stable, shorter than usual oligonucleotides.
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How do LNA-based drugs differ from siRNA drug candidates?
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LNA oligonucleotides are short, single stranded and can be delivered into the cells without additives. siRNA drugs are longer, double stranded and face delivery problems.
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Where is Santaris Pharma situated?
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The Company is headquartered in the science park SCION DTU in Hørsholm close to Copenhagen, Denmark's capital.
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When was the company founded?
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Santaris Pharma was founded in 2003 through a merger between two Danish biotecnology companies.
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